Download the GLYcoDiag’s Newsletter October 2020 about Neoglycoproteins NeoGalf and NeoGalili.
Laminarin Effects, a β-(1,3)-Glucan, on Skin Cell Inflammation and Oxidation
Ozanne, H., Toumi, H., Roubinet, B., Landemarre, L., Lespesailles, E., Daniellou, R., Cesaro, A., Cosmetics, 2020, 7, 66.
GLYcoPROFILE was recently used to evaluate on cutaneous cells (i.e. NHDFa and NHEK) the effect of Laminarin, a β-(1,3)-glucan from the seaweed Laminaria digitata, polysaccharide which provides anti-inflammatory and anti-oxidative properties.
This study is another example of the powerfull interest to use the GLYcoPROFILE technology to investigate biological properties of glycomolecules.
Download the GLYcoDiag’s Newsletter September 2020 about cells GLYcoPROFILE.
Download the GLYcoDiag’s Newsletter June 2020 about our original lectins (cMol, BanLec, TXLC-I and CorM)
Download the GLYcoDiag’s Newsletter May/June 2020 about our list of recombinant lectins.
Queiroz, A., Landemarre, L., Vial, F., Aubert, A., IFSCC Magazine 1 2020
The GLYcoPROFILE® study was used recently in the development of a new cosmetic ingredient developped by Seqens. This study highlights the ability of a high molecular weight exopolysaccharide to provide a quantifiable benefit versus placebo by visibly enhancing not only the quality of the skin tissue but also the consumer’s emotional state. In fact, the GLYcoPROFILE have enabled to highlight specific interaction with rhamnose specific lectin (lectin CorM which recognizes rhamnosylated glycan structures in the same manner as rhamnose-specific protein expressed at the surface of keratinocytes and fibroblasts). Apart from the fact that rhamnose glycan motif recognition is known to interfere with cells and epidermal regeneration, thus having anti-aging and anti-inflammatory properties, rhamnose recognition is known to enhance beta-endorphin release by keratinocytes and improve the feeling of wellbeing.
Senecar, M., Lafite, P., Eliseeva, S. V., Petoud, S., Landemarre, L., Daniellou, R., Int. J. Mol. Sci. 2020, 21, 3465; doi:10.3390/ijms21103465
Galactofuranose is a rare form of the well-known galactose sugar, and its occurrence in numerous pathogenic micro-organisms makes the enzymes responsible for its biosynthesis interesting targets. This review summarizes the role of these carbohydrate-related proteins with a special emphasis on the galactofuranosidases recently characterized as an efficient recombinant biocatalyst.
Download the GLYcoDiag’s Newsletter April/May 2020 about our new distributor and information about COVID-19 glycosylation
Download the GLYcoDiag’s Newsletter March 2020 about the development of NeuGc specific lectin HPyL and the potential applications.
Download the GLYcoDiag’s Newsletter February 2020 to learn more about GLYcoPROFILE, a method used to predict potential biological activities.