Download the GLYcoDiag’s Newsletter May/June 2020 about our list of recombinant lectins.
Queiroz, A., Landemarre, L., Vial, F., Aubert, A., IFSCC Magazine 1 2020
The GLYcoPROFILE® study was used recently in the development of a new cosmetic ingredient developped by Seqens. This study highlights the ability of a high molecular weight exopolysaccharide to provide a quantifiable benefit versus placebo by visibly enhancing not only the quality of the skin tissue but also the consumer’s emotional state. In fact, the GLYcoPROFILE have enabled to highlight specific interaction with rhamnose specific lectin (lectin CorM which recognizes rhamnosylated glycan structures in the same manner as rhamnose-specific protein expressed at the surface of keratinocytes and fibroblasts). Apart from the fact that rhamnose glycan motif recognition is known to interfere with cells and epidermal regeneration, thus having anti-aging and anti-inflammatory properties, rhamnose recognition is known to enhance beta-endorphin release by keratinocytes and improve the feeling of wellbeing.
Senecar, M., Lafite, P., Eliseeva, S. V., Petoud, S., Landemarre, L., Daniellou, R., Int. J. Mol. Sci. 2020, 21, 3465; doi:10.3390/ijms21103465
Galactofuranose is a rare form of the well-known galactose sugar, and its occurrence in numerous pathogenic micro-organisms makes the enzymes responsible for its biosynthesis interesting targets. This review summarizes the role of these carbohydrate-related proteins with a special emphasis on the galactofuranosidases recently characterized as an efficient recombinant biocatalyst.
Download the GLYcoDiag’s Newsletter April/May 2020 about our new distributor and information about COVID-19 glycosylation
Download the GLYcoDiag’s Newsletter March 2020 about the development of NeuGc specific lectin HPyL and the potential applications.
Download the GLYcoDiag’s Newsletter February 2020 to learn more about GLYcoPROFILE, a method used to predict potential biological activities.
Download the GLYcoDiag’s Newsletter January 2020 about the recombinant prokaryotic lectins (RPLs) from GlycoSeLect.
The Glycosciences products catalogue 2019 are now available to download.
Cauwel, M.; Sivignon, A.; Bridot, C.; Nongbe, M. C.; Deniaud, D.; Roubinet, B.; Landemarre, L.; Felpin, F.-X.; Bouckaert, J.; Barnich N.; Gouin, S. G.; Chem. Commun., 2019, 55, 10158-10161 .
The development of a chemical method to covalently functionalize cellulose nanofibers and cellulose paper with mannoside ligands displaying a strong affinity for the FimH adhesin from pathogenic E. coli strains was studied. Mannose-grafted cellulose proved efficient to selectively bind FimH lectin and discriminate pathogenic E. coli strains from non-pathogenic ones. FimH LEctPROFILE plates was used in this study to evaluate the effect of the mannose-grafted cellulose compound over FimH lectin.
GLYcoDiag is beneficiary of the LectARRAY ANR project (PRCE) in collaboration with CERMAV (project coordinator: Dr. Varrot), DCM (Dr Renaudet) and IBS (Pr. Fieschi) institutes. LectARRAY aim to developp lectin array applications for glycoanalysis of biopharmaceuticals.