GLYcoDiag offer cosmetic ingredient evaluation through it’s two specialities: Microbiote and Glycosciences. Ingredient activities on skin microbiote can be demonstrated on specific co-culture models mimicking skin environments in order to know the ability of your product to modulate: (1) diversity and growth of microbiota, (2) adhesions of respective microbial strains on corneocytes, (3) protect microbiote from environmental stresses. Moreover, our own technology platform GLYcoPROFILE®, allows to determine interaction profiles of « glyco-actives » ingredients with glycans binding proteins thus anticipating afterwards on potential biological properties relevant for cosmetic applications.

For your information, we are exhibiting at in-cosmetics Global 2024. We are pleased to invite you to meet us on our stand 1R64A by following the link below. We will be delighted to share and present you in more details the last service innovations mentioned above devoted for your cosmetic ingredients development.
Direct link : https://registration.iceni-es.com/in-cosmetics/?dc=GLY-849203
Invite code : GLY-849203

GLYcoDiag develop it’s own range of research reagents and kits dedicated to Glycosciences and add new reference every years in order to offer to our customer the most original, innovative and better quality products:
– Natural and recombinant lectins;
– Neoglycoproteins;
– LEctPROFILE® affinity chromatography supports;
– LEctPROFILE® kits for evaluation of crude or purified glycoconjugates interactions with lectins.
The full list of these reagents are available directly on our website at: https://www.glycodiag.com/products

Don’t hesitate to contact us, to obtain the 2024 GLYcoDiag products catalogue or for a quotation.

We are exhibiting at in-cosmetics Global 2024. We are pleased to invite you to meet us on our stand 1R64A by following the link below :
Direct link : https://registration.iceni-es.com/in-cosmetics/?dc=GLY-849203
Invite code : GLY-849203
We will be delighted to share our last service innovations in glycosciences and microbiote area, intended for cosmetic applications.

Since it’s creation, GLYcoDiag has proposed several miniaturized methods (Micro-challenge test, Time-to-kill study, Minimal inhibitory concentration (MIC), Co-culture studies and microbiota skin adhesion) to accelerate the development of your cosmetic actives. The 2024 pricing of these standardised methods are now available with a slight but controlled increase due to our supplier’s costs changes. However, we decided this year to maintain the Micro-challenge test price similar to last year. Indeed, in a period of inflation, this was only possible with a strong control of the reagents and consumables costs by our team.

Don’t hesitate to contact us to obtained more informations and/or a quotation about these analyses.

Since its creation in 2005, GLYcoDiag has continuously extended its expertise in the field of glycoscience in order to propose you ever more innovative services and products that suits your needs.

Studies:

Use GLYcoPROFILE plateform for:

– Identify glycans signature of your therapeutic recombinant glycoproteins for in-process reference sample comparison, batch to batch monitoring, glycoforms specific profiles or immunogens glycans detection.

– Study glycome expression and accessibility for the research of new glyco-biomarkers.

– Search and characterize new glycosylated related drugs or molecule and anticipate potential actionon biological mechanism.

– Study the effect of products on glycobiological interactions between microorganisms and cells (Glycomicrobiote studies).

Glycoanalytics.

– Complementary to our GLYcoPROFILE plateform we propose several standard glycoanalysis to know more about the structure of your product: O- and N-glycans, Sialic acid composition, neutral monosaccharide composition, and molecular weight.

Products:

GLYcoDiag develop it’s own range of research reagents and kits dedicated to Glycoscience and add new reference every years in order to offer to our customer the most original, innovative and better quality products:

– Natural and recombinant lectins;

– Neoglycoproteins;

– LEctPROFILE^® affinity chromatography supports;

– LEctPROFILE^® kits for evaluation of crude or purified glycoconjugates interactions with lectins.

The full list of these reagents are available directly on our website at: https://www.glycodiag.com/products

Don’t hesitate to contact us, if you need: (1) further information about GLYcoDiag’s services and products, (2) a quotation.

As you know GLYcoDiag provides it’s micro-challenge test services from more than 10 years. Compared to the standard method, the GLYcoDiag’s micro-challenge test is a high throughput, cost effective and the method of choice for research projects aiming at the development of new system preservatives or the control steps of anti-microbial efficacy where the regulatory method is not absolutely required. Now, we propose two additional upgraded models of our micro-challenge test method:
(1) Re-challenge testing. Repeated inoculation with specific test micro-organisms can show the number of contamination challenges a product can withstand before the preservative system fails for the micro-organism studied.
(2) Mixed. In this study, the goal is to compare and determine the efficiency of a preservative with a mixture of microbial strains (fungi and bacteria), in a more complex environment model.

Next micro-challenge test studies will be launched in week S6 (reception of products before the end of week S5).

Dear customers,

As you know, GLYcoDiag propose several miniaturized methods in microbiology which help you during the development stages of your ingredients. The methods listed below enable to study the potential antimicrobial properties of a product (alone or in combination) on a large range of bacteria and fungi.

Those methods are devoted to:

– Determine the minimal inhibitory concentration (CMI).

– Design boosters, systems preservatives or identification/optimization of synergy effects through micro-challenge test method. As a reminder, micro-challenge test is the method of choice for all steps where the regulatory method is not absolutely required (ISO11930). Moreover, adapted to various products viscosities, the micro-challenge test can help you to accelerate your development through large screening with different formulations. Finally, the micro-challenge test method can be customized according to your needs (strains and picking time).

– Evaluate the rate of microbial decrease through Time to kill study.

We remain at your disposal for any further information regarding these services or for a quotation.

With best regards,

GLYcoDiag

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