The Glycosciences products catalogue 2019 are now available to download.
Cauwel, M.; Sivignon, A.; Bridot, C.; Nongbe, M. C.; Deniaud, D.; Roubinet, B.; Landemarre, L.; Felpin, F.-X.; Bouckaert, J.; Barnich N.; Gouin, S. G.; Chem. Commun., 2019, 55, 10158-10161 .
The development of a chemical method to covalently functionalize cellulose nanofibers and cellulose paper with mannoside ligands displaying a strong affinity for the FimH adhesin from pathogenic E. coli strains was studied. Mannose-grafted cellulose proved efficient to selectively bind FimH lectin and discriminate pathogenic E. coli strains from non-pathogenic ones. FimH LEctPROFILE plates was used in this study to evaluate the effect of the mannose-grafted cellulose compound over FimH lectin.
GLYcoDiag is beneficiary of the LectARRAY ANR project (PRCE) in collaboration with CERMAV (project coordinator: Dr. Varrot), DCM (Dr Renaudet) and IBS (Pr. Fieschi) institutes. LectARRAY aim to developp lectin array applications for glycoanalysis of biopharmaceuticals.